How would you manage primary breast osteosarcoma?

Osteosarcoma of the breast is a rare and highly aggressive tumor, accounting for less than 1% of all primary breast malignancies. Due to its infrequent occurrence, there is a lack of prospective studies to determine the best treatment approach and most publications are case reports. Instead of focus...

For a de novo breast sarcoma including a malignant phyllodes tumor (with stromal overgrowth), depending on host factors (age, PS, organ function, etc.) and tumor factors (grade, size), the treatment options would include local therapy (preop XRT followed by WLE for low-risk tumors) or consideration ...