How would you manage serum sodium monitoring for an asymptomatic outpatient with newly diagnosed SIADH and a serum sodium level of 127 mEq/L, for whom you are initiating treatment with urea?

Based on the current available data, treatment of SIADH with urea is effective with a very low risk of overcorrection. In a meta-analysis of 23 studies involving 537 patients with SIADH, urea increased serum sodium concentration by a mean of 9.6 mmol/L, and the mean increase in serum sodium after 24...

I would start urea and check a serum Na in two weeks.