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How would you manage the primary site of a metastatic nasopharyngeal cancer showing cCR after systemic therapy?

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Radiation Oncology · Moffitt Cancer Center

Small phase III randomized trial of metastatic nasopharyngeal cancer patients with a CR/PR by imaging after 3 cycles of cisplatin/5FU showed that RT+chemo (primary/nodes + elective nodes) had an overall survival advantage compared with chemotherapy alone (You et al., PMID 32701129).

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How would you manage the primary site of a metastatic nasopharyngeal cancer showing cCR after systemic therapy? | Mednet