How would you manage tubulointerstitial nephritis and renal tubular acidosis (RTA) in a patient with Sjogren's who is pregnant?

Topics: Rheumatology • General Rheumatology • Sjogren’s syndrome • Pregnancy • Nephrology • Renal Tubular Acidosis

Answer from: at Community Practice

The most common form or renal disease in Sjogren's (SjD) is tubulointerstitial nephritis. This may result in tubular dysfunction leading to renal tubular acidosis (RTA), most commonly type I RTA leading to hypokalemia and a non-anion gap hyperchloremic acidosis. Over time, nephrocalcinosis can occur...

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at Montefiore Medical Center
Thank you for your thoughtful answer. What would y...

Answer from: at Community Practice

I have seen quite a few RTAs in my obstetric nephrology fellowship. Potassium citrate requirements tend to increase throughout pregnancy so will need frequent assessment and adjustment.

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