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How would you proceed when a cervical cancer undergoing brachytherapy has exceeded the rectal dose but not met the target dose?

2 Answers
Mednet Member
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

Rectal dose and target dose have range.

Preferred rectal dose for D2cc < 65 Gy but can accept up to D2cc < 75 Gy, provided you understand expected risk of complications with increased dose.

Preference would be to do hybrid applicator with 3D imaging to optimize HRCTV and OAR.

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Mednet Member
Mednet Member
Radiation Oncology · Vanderbilt-Ingram Cancer Center

Priority, for me, would be to treat the cancer, at least to a D90 EQD2 minimum of 80 (goal of > 85) as per EMBRACE data, if residual disease > 4cm at time of brachytherapy. If < 4cm, then would be content with EQD2 > 80.

While IGBT and consideration of hybrid approach, if possible, are ideal options ...

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How would you proceed when a cervical cancer undergoing brachytherapy has exceeded the rectal dose but not met the target dose? | Mednet