How would you reconcile EQD2 calculation for organs at risk in patients receiving BID fractionation to the chest after an initial course of daily conventional fractionation?

Topics: Radiation Oncology • Thoracic Malignancies

E.g treating and SCLC after prior NSCLC.

Answer from: Radiation Oncologist at Community Practice

There is a paper regarding time-based corrections to BED for hyperfractionation in such a scenario. You end up multiplying the usual result by a time factor that increases the BED above the usual daily fraction result. I don't have the reference handy but it is out there. Maybe someone else on this ...

Comments

Radiation Oncologist at Washington University/Barnes-Jewish Hospital
I think the time adjusted-BED formulas that were u...

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