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How would you treat a biopsy-proven isolated uterine cervix metastasis of adenocarcinoma from a known colon cancer primary, previously stage IIIb at diagnosis two years prior?

Surgical path confirmed CK7(-), CDX2(+), CK20(+), consistent with prior colonic adenocarcinoma.
2 Answers
Mednet Member
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Radiation Oncology · Sunnybrook Health Sciences Centre
Answered on

We have dealt with few similar cases in the past few years. The overall management will depend on the patient's prior history - did she get any neo-adj or adj radiation within the pelvis for prior cancer? How large is the cervix metastasis? A multi-disciplinary management is paramount with involveme...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

We usually prefer surgery and if surgery is not possible, then xeloda plus RT for downsizing and then surgery, and the last option is definitive chemo RT.

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