How would you treat a locally recurrent triple negative breast cancer after achieving CR a year earlier to neoadjuvant ddAC-T, BCS and WBRT?

I would recommend staging work up to rule out distant metastases for this patient with high-risk TNBC before committing this patient to local therapy.

Isolated Loco-regional recurrences (ILRR) are associated with a high risk of developing distant metastases and early recurrence (< 24 months, as in th...