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What would be an appropriate chemotherapy de-escalation strategy for patients with metastatic TNBC on pembrolizumab/chemotherapy with CR and negative ctDNA?

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Mednet Member
Mednet Member
Medical Oncology · Warren Alpert Medical School of Brown University

My inclination would be to stop the chemotherapy but continue pembrolizumab indefinitely, in the absence of an immune-related adverse event (that can't be easily controlled, such as hypothyroidism).

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