How would you treat a synchronous low rectal adenocarcinoma and anal squamous cell carcinoma with involved pelvic and inguinal nodes?  

What systemic therapy is most appropriate, how would you sequence, and what RT dose fractionation would you use?



Answer from: Radiation Oncologist at Community Practice

Answer from: Medical Oncologist at Community Practice

Answer from: Radiation Oncologist at Academic Institution
Comments
Radiation Oncologist at Mallory Radiotherapy, PLLC
It sounds like the big question/controversy is whe...
Radiation Oncologist at Washington University School of Medicine
Presumably, you're considering taking the anal pri...
Radiation Oncologist at Mallory Radiotherapy, PLLC
Moreso a watch-and-wait approach is pursued if the...
Radiation Oncologist at Washington University School of Medicine
I would agree with a watch-and-wait approach for t...
Radiation Oncologist at Mayo Clinic School of Medicine
This is a really great discussion. I have a couple...
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Answer from: Medical Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice
Comments
Radiation Oncologist at Mallory Radiotherapy, PLLC
Thank you for referencing this recent data. I have...
Radiation Oncologist at Sunnybrook Health Sciences Centre
We have previously used up to 63 Gy and have not w...
Radiation Oncologist at Cape Oncology
What small bowel dose would you accept in this cas...
Radiation Oncologist at Sunnybrook Health Sciences Centre
At our institution, the protocol is bowel space (b...
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Answer from: Medical Oncologist at Community Practice