How would you treat a young patient with good performance status who has de novo metastatic HR+ Her2+ inflammatory breast cancer with asymptomatic leptomeningeal and CNS parenchymal disease?
Answer from: Medical Oncologist at Academic Institution
If her CNS parenchymal disease is low burden and amenable to SRS I would do that first. Then place an Ommaya followed by initiation of TPH plus ovarian suppression. Finally, would begin concurrent weekly IT trastuzumab 20mg with regular monitoring of CSF for clearance of cells plus follow up b...
Comments
Medical Oncologist at Providence Western Washington Onc, Inc Both Neratinib and Tucatinib Have recently good s...
Both Neratinib and Tucatinib Have recently good s...