Mednet Logo
HomeHematologyQuestion

How would you treat an elderly fit patient with stage IE DLBCL (single skin lesion)?

1
2 Answers
Mednet Member
Mednet Member
Medical Oncology · Christie NHS Foundation Trust

Is this a primary cutaneous large B-cell lymphoma, leg type? I suspect so. This is a rare and aggressive disease. I would carefully stage the patient ( to include bone marrow ) and treat as per any localised DLBCL with 3-4 cycles R-CHOP and XRT. Even with this regimen 50% of patients relapse so I'd ...

Register or Sign In to see full answer

Mednet Member
Mednet Member
Medical Oncology · University of California Irvine

Assuming DLBCL, leg type there is also precedent for local XRT after thorough staging with close follow up. It is imperative to have the pathology reviewed by an expert hematopathologist in cutaneous lymphomas.

Register or Sign In to see full answer