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How would you treat an isolated urothelial cancer local recurrence abutting the duodenum?

What dose/volume would you use in a young, fit patient with an isolated local recurrence (abutting the duodenum) of an upper tract urothelial cancer 4 months post-nephrectomy?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · University of Kentucky
Answered on

My first question would be "why not surgery?" This would be my preferred approach unless there is some contradiction to surgery that I am unaware of. If surgery is contraindicated, I would use a conventionally fractionated approach and try to get to a dose of 5,940 cGy, but this would be following a detailed informed consent discussion with the patient, well-documented in the chart, regarding the risk that this entails as opposed to the risk of using a suboptimal dose in this "young, fit" patien...

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