How would you treat isolated axillary recurrence of a previously node negative ER/PR+, HER2- breast cancer after prior neoadjuvant chemotherapy, lumpectomy/adjuvant RT, and adjuvant AI?
The recurrence was 2 years after treatment with ddAC + T. If you elect for systemic therapy after local therapy, what chemotherapy would you use given exposure to ACT already?
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3 Answers
Mednet MemberInvited Expert
Medical Oncology · Baptist Health South Florida
Answered on
The problem of isolated local or regional recurrence has been a vexing one for years. There have been multiple attempts to complete a randomized trial with sufficient numbers to draw conclusions and none have succeeded. I was Principal Investigator for one such Intergroup trial in the 1980's closed ...
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Mednet MemberInvited Expert
Medical Oncology · Baptist Health South Florida
Answered on
proviso. Since the relapse was greater than a year after start of A.I. one could consider reintroduction of an A.I. rather than Fulvestrant.
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Mednet Member
Medical Oncology · Capital Region Southwest Campus
Answered on
Fosladex plus ibrance
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