How would you treat pelvic node recurrence after prior RP and adjuvant XRT prostate bed only?
Given interim analysis of PEACE V-STORM; also institutional data from SHARP consortium of using 25 Gy/5 fx for pelvic lymphatics. Can we extrapolate?
Answer from: Radiation Oncologist at Community Practice
When we first started treating pelvic nodal recurrence, we used to treat involved-field with SBRT at a dose of 35 Gy in 5 fractions. We rapidly realized that some patients relapse elsewhere in the pelvis. We then started to add elective nodal irradiation with integrated boost to the involved nodes. ...
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Radiation Oncologist at Hôtel Dieu de Lévis - CISSS Chaudière-Appalaches Would you consider intensifying with Abiraterone (...
Radiation Oncologist at Universite de Montreal It's a good question. In Québec, Abirateron...
Radiation Oncologist at Hôtel Dieu de Lévis - CISSS Chaudière-Appalaches Thank you!
Answer from: Radiation Oncologist at Community Practice
At Karmanos, we will frequently use proton therapy when re-irradiating the pelvis for nodal relapses, to minimize the exit dose to the midline structures of bladder, bowel, sigmoid and rectum, and reduce overlap with prior prostate/prostate bed doses. A common salvage dose is 35-40 Gy in 5 fractions...
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Radiation Oncologist at Mayo Clinic Dr. @Hyde, regarding your final paragraph: in your...
Radiation Oncologist at Karmanos Cancer Institute - McLaren Proton Therapy Center For spinal cord, I usually insist on 6 months or m...
Radiation Oncologist at Stony Brook University School of Medicine How do you account for doses to the lumbosacral pl...
Answer from: Radiation Oncologist at Academic Institution
I try to get the previous DICOMs to create a sum plan, with fusion of previous plan based on bony anatomy. If DICOMs are unavailable, an attempt to reconstruct the previous fossa salvage plan should be made.I don't have a hard threshold of requiring a certain gap, but I do evaluate the sum plan and ...
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Radiation Oncologist at Lafayette Radiation Center Elective nodes with boost - SBRT or modhypo or std...
Answer from: Radiation Oncologist at Academic Institution
Some great answers in this thread.
We also offer 25 fractions (45 Gy elective; 55-60 Gy SIB involved) or 5 fractions (25 Gy elective; 30-40 Gy involved) salvage RT routinely.
The question of volumes is a good one since there's growing data that just SBRT to a single node (if no prior elective RT i...
Answer from: Radiation Oncologist at Academic Institution
Nodal recurrences after definitive local therapy can be complicated, and I think the devil is in the details. There is clearly a range of acceptable treatments. If you have a solitary node recurring 10 years after RP and salvage XRT with a PSA doubling time of 5+ years in a 75+ y/o, then SBRT to jus...
Would you consider intensifying with Abiraterone (...
It's a good question. In Québec, Abirateron...
Thank you!