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How would you treat recurrent endometrial carcinoma with a presentation of inguinal and external iliac adenopathy?

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3 Answers
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Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

I would treat with definitive intent with either surgery followed by (chemo) RT or definitive (chemo) RT targeting the pelvic at least up to the common iliac and bilateral inguinal region.

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Mednet Member
Mednet Member
Radiation Oncology · Vanderbilt-Ingram Cancer Center

Presumable post-surgical recurrence without receipt of previous RT. Is there a vaginal recurrence as well in or extending to the distal vagina, which could explain the inguinal nodes? Are the nodes PET-positive or biopsy-proven?

If this is purely a nodal recurrence, no reason to think distal vaginal...

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Radiation Oncology · Allegheny Health Network

If not already done, I would get PET/MRI and do an EUA with gyn onc to rule out vaginal recurrence as @Dr. First Last noted.

Then I would treat with definitive intent RT with chemo if able. I would follow that with carbo taxol if tolerable +- IO with consideration of MMR status.

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How would you treat recurrent endometrial carcinoma with a presentation of inguinal and external iliac adenopathy? | Mednet