How would you treat systemic polyarteritis nodosa with orchitis, mononeuritis and glomerulonephritis in a person who is being treated for HiV with low level viremia?

Difficult situation but there is a clear need to make decisions and balance somewhat unquantifiable risks. It is always good to remember that polyarteritis nodosa is quite rare. One should ensure the diagnosis is confirmed with, preferably, both a positive biopsy of one of the affected areas and neg...

PAN is a systemic necrotizing vasculitis that preferentially targets medium-sized arteries and as such is not generally associated with glomerulonephritis. I would carefully review the workup to ensure that you have the right diagnosis.