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How you approach treatment of a glioblastoma in the setting of prior WBRT for a metastatic non-CNS malignancy?

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Radiation Oncology · Mayo Clinic Florida
Answered on

I think treatment to 25 Gy in 5 fractions or 40 Gy in 15 fractions to areas of enhancement and/or post-op bed can be safely delivered after whole brain (assuming the patient was treated to 30 Gy in 10 fractions). We commonly treat with SRS after whole brain RT. Just be cognizant of cumulative dose t...

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