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If small cell carcinoma was found in an axillary lymph node with an unknown primary, would you recommend axillary lymph node dissection prior to chemoradiation?

2 Answers
Mednet Member
Mednet Member
Radiation Oncology · Memorial Sloan Kettering Cancer Center

Just to be clear, is this a patient with lung cancer? I know this is posted in the thoracic section, and has been responded to by a thoracic specialist, but usually “small cell carcinoma” in axillary lymph nodes without disease (especially in the thorax) elsewhere is Merkel cell carcinoma (cutaneous...

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Mednet Member
Mednet Member
Radiation Oncology · University of Texas MD Anderson Cancer Center

I would not recommend axillary lymph node dissection for metastatic ancillary lymph node small cell carcinoma. Surgery has not been proven to improve OS for metastatic small cell lung cancer. In addition, it carries significant co-morbidities such as arm edema. I would recommend chemotherapy, follow...

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