In a patient who requires prostate cytoreduction prior to EBRT or brachytherapy, do you include a 5-alpha reductase inhibitor in your ADT regimen?

This is a great question. Although 5-aplha reductase inhibitors do shrink the prostate, there is little data reporting on its use prior to RT.

Jethwa et al (J of Contem Brachytherapy 2016 Oct; 8(5): 371–378.) evaluated factors that impacted decrease in prostate volume and the initial prostate volu...