In a patient with a history of HIT, how would you reintroduce Heparin?
1 Answers
Mednet Member
Hematology · Weill Cornell Medical College and Houston Methodist Hospital
When patients with even remote histories of HIT are re-exposed to heparin, there is a very high risk of heparin-PF4 antibody seroconversion (Warkentin and Anderson, PMID 27114458). I have seen two patients who suffered a fatal relapse of HIT (e.g., case one in Kodityal et al., PMID 12890149). Bivali...