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In a patient with APS and obesity during pregnancy when switched to LMWH, do you cap the dose of dalteparin as per manufacturers labeling at 18,000U per day or do you use weight based dosing?

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Mednet Member
Mednet Member
Hematology · Indiana Hemophilia and Thrombosis Center

Hi @Dr. First Last,

We use enoxaparin in our institution, but the general principle that we follow is that we do not cap LMWH dose at a set threshold. I am assuming that you're referring to thromboprophylaxis and not the management of a VTE in the past 6 months.

We monitor anti-Xa levels in obese p...

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