In a patient with ER/PR positive metastatic breast cancer with CNS disease progression on tamoxifen, would you consider AI+ palbo or capecitabine?

The options for treating a patient like this could depend on a number of factors. For example, the number of brain metastases, patient performance status and level of control of extracranial disease at the time of CNS progression.

In general, if a patient has good response to the systemic disease, t...