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What adjuvant therapy would you recommend for a premenopausal woman with low ER+/PR+ (1-10%) HER2- pT1cN0 metaplastic breast cancer?
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Mednet Member
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
The rarity of the metaplastic subtype of breast cancer makes it difficult to provide an evidence-based answer regarding what is the "best" adjuvant treatment. About 70% of metaplastic tumors are TNBC and ER-low is a small subset of the remaining 20% with an ER+ epithelial component. In general, some...
Mednet Member
Medical Oncology · Warren Alpert Medical School of Brown University
While I agree with Dr. @Dr. First Last that I would recommend that this patient receive adjuvant chemotherapy and that I would treat her as having triple-negative disease, as I would a patient with an ER-low invasive ductal carcinoma, I would definitely treat her with weekly paclitaxel and carboplat...