In a patient with stage III-IV p16+ oropharyngeal cancer undergoing definitive CRT who is unable to maintain nutrition, would you rather consider stopping treatment early (to an investigational de-escalated dose) or insert a feeding tube/take treatment breaks in order to complete the full dose?

Off protocol, we should complete the course of chemo radiation, so feeding tube if needed.

I agree with Dr. @Dr. First Last. I would push to complete the course of chemoradiotherapy and not stop early.

I too would not hesitate to place a feeding tube during therapy. Ideally, this is a PEG if it is anticipated that the patient will require nutritional support for any length of time. Otherw...