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In DCD liver offers where NRP or hypothermic oxygenated perfusion is available, what donor/recipient factors are still absolute or near-absolute reasons to decline because of ischemic cholangiopathy risk?

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Is machine perfusion available and routinely performed at your institution?

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1 Answer
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Hepatology · Mount Sinai Hospital
Answered on

Since the advent and subsequent rapid development of machine perfusion techniques, liver transplant programs are ever-broadening their consideration of previously thought to be "extended" donors. Risks of ischemic cholangiopathy may be linked to the expertise of the program in using machine perfusion. Hepatic artery stenosis and subsequent biliary ischemia may be related to technical issues in connecting the vasculature with the perfusion device. Donors who have already had periods of hypotensio...

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