Mednet Logo

In mismatch repair deficient recurrent endometrial cancer eligible for single agent PD-1 inhibitor, do you prefer pembrolizumab or dostarlimab and why?

Community PollStarted

In dMMR recurrent endometrial cancer eligible for single agent PD-1 inhibitor, do you prefer pembrolizumab or dostarlimab and why? (select the agent and select your rationale)

35 physicians have voted

Join Mednetto vote and see how they answered.

1 Answer
Mednet Member
Mednet MemberInvited Expert
Gynecologic Oncology · UCLA David Geffen School of Medicine/UCLA Medical Center
Answered on · Updated on

From KEYNOTE-158, single agent Pembrolizumab (anti-PD1) in dMMR recurrent endometrial cancer patients (N=79), ORR 48% (14% CR and 34% PR). Median PFS was 13.1 months. In this study, adverse events happened in 76% of patients. 12% had G3-4 toxicity. 7% discontinued for toxicities. 7% had G3-4 immunot...

Join for free or sign in to see the full answer