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In oral cavity cancers, how does WPOI (worse pattern of invasion) influence your decision to offer adjuvant therapy?

For a patient with pT2N0 oral tongue cancer and no other adverse risk features (no LVI or PNI), would WPOI 4 or 5 be enough to offer adjuvant radiation?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on

It doesn’t.

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Currently, it doesn’t change recommendations without any other adverse factor. So the above case would favor observation.

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