In patients with anti-PL7 antibody–associated antisynthetase syndrome, can sacroiliitis occur as part of the inflammatory arthritis spectrum, or should alternative causes be considered?

A review of the literature on large cohorts of antisynthetase syndrome does not report sacroiliitis as a feature, but rather, inflammatory arthritis similar to rheumatoid arthritis (with or without RF and CCP) is described. Therefore:

1. It is important to confirm whether the PL-7 result is truly posi...