In patients with severe hemophilia A on emicizumab for prophylaxis, in case of noncompliance leading to a lapse of more than 2-3 months off therapy, do you reload with emicizumab?

Topics: Pediatric Oncology • Hemostasis • Hematology • Pediatric Hematology • Benign Hematology • Hemophilia

Answer from: at Academic Institution

In general, you need to restart the four-week loading then follow with maintenance. First, you need to find out why they were noncompliant (e.g. did not like/could not do subcutaneous injections, did not work, always noncompliant). If they are planning to continue noncompliance, this is not a...

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at Rochester General Hospital
Thank you, Dr. @Margaret Ragni. All these are ver...

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