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In patients with severe osteoporosis, history of retinal artery occlusion, and hypercalciuria, would you favor PTH analogue therapy or Evenity?

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In a patient with severe osteoporosis, a history of retinal artery occlusion, and hypercalciuria, would you favor a PTH analog or romosozumab (Evenity)?

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1 Answer
Mednet Member
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Endocrinology · Milwaukee Va Medical Center
Answered on

Assuming that PTH and vitamin D are normal, neither. Chlorthalidone is the treatment of choice in this scenario. Chlorthalidone is usually better than HCTZ, as HCTZ often must be given BID, whereas chlorthalidone can be given daily. I have seen very large improvements in BMD with thiazide therapy, o...

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