In the post-mastectomy setting, are there situations where only the regional nodes or targeted nodal basis are covered?

Thanks for asking this question. People occasionally ask this.

1. Essentially all of the trials that show a survival advantage with PMRT used comprehensive local-regional therapy. So, doing something other than both the chest wall and nodes would not be based on the available data.
2. Cancer is sneaky, i...

In the AMAROS study, they did allow regional nodal RT without treating the chest wall for a situation like this. In practice, I have avoided this unless morbidity is high like impact on reconstruction or it is in a reradiation setting.

Born too late to explore the earth, born too early to explore the stars, burn just in time to use 2024 technology to deliver treatment based on 1994-quality data.

Laying aside the "ECE" issue for a second, I think these are reasonable questions to ask in the era of modern systemic therapy. I think i...