In the rare setting of enoxaparin injection-induced abdominal wall hematoma in patients requiring long-term anticoagulation, what is your timeline for restarting anticoagulation?

Abdominal wall hematomas typically occur when a vessel has inadvertently been injured during injection. Timing of resumption of anticoagulant will vary with the underlying indication for anticoagulants. For a high-risk indication, eg multiple cardiac valves in patients with history of stroke, I would consider resuming after 24 hours and even then consider going to IV unfractionated heparin (provided there is a reasonable degree of certainty of hemostasis). May have to delay to 48 hours. Short ha...