In the setting of an atypical lipoma/well-differentiated liposarcoma of the extremity with a small component of dedifferentiated liposarcoma, is it necessary to treat the entire mass with neoadjuvant radiotherapy OR just the dedifferentiated component that is enhancing on contrast MRI?

When treating these well-differentiated liposarcomas, I would treat the entire mass to the preop dose of 50 Gy in 25 fx. Although there may be visible areas of dedifferentiated on MRI, there may be other areas that are not visible on imaging, and thus treatment of the entire mass would be warranted....