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In what clinical scenario, if any, would you consider APBI appropriate treatment for a patient with triple-negative breast cancer?

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Mednet Member
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

Currently, none of the prospective studies did APBI after neoadjuvant chemotherapy so that subset, we don't offer APBI (need studies in this space).

As far as denovo early-stage TNBC, we have not been doing APBI as were only part of one (B39) of all prospective randomized studies with PBI and also sh...

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Mednet Member
Mednet Member
Radiation Oncology · Abramson Cancer Center, University of Pennsylvania

Agree regarding PBI after NAC with @Dr. First Last.

We only offer whole breast radiation after neoadjuvant therapy for TNBC. Although, I suspect it’s one of these ‘it might be fine’ things, but we still won’t do it.

But we have chosen to offer PBI for small ER negative disease who have received approp...

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In what clinical scenario, if any, would you consider APBI appropriate treatment for a patient with triple-negative breast cancer? | Mednet