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Topics:
Pediatric Hematology/Oncology • Hematology • Sickle Cell • Pediatric Hematology • Hepatology • Genetic Liver Disease
In what clinical scenario would you consider liver transplant evaluation for a patient with sickle cell hepatopathy?
And should this be considered in conjunction with or sequentially with a bone marrow transplant as the actual cure for underlying hematologic disease?
Answer from: at Academic Institution
We have evaluated and transplanted patients with sickle cell hepatopathy with severe liver dysfunction but well-controlled sickle cell. These patients will typically have jaundice, coagulopathy, and biliary strictures. They should not have significant extrahepatic complications of the hematologic di...
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