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In what N1 H&N patients, if any, would you consider treating the gross disease (primary + involved node) only without elective nodal radiation volume with definitive intent in order to reduce toxicity?

Can elective nodal RT be omitted for select patients with T2-4N1 head and neck cancers with multiple commodities and poor KPS with life expectancy <3 yrs who are not candidates for chemo based on the rationale that the toxicity may outweigh any benefit?
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Would you consider omitting elective volume infinitive H&N radiation for N+ patients?

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2 Answers
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Radiation Oncology · University of Florida
Answered on

Madness. Not just no but bleep no. I don’t want to injure a lot of patients and discover something stupid.

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan Kettering Cancer Center
Answered on · Updated on

Generally, we try to give patients the benefit of doubt and treat locally advanced disease with curative intent therapy. If one is uncomfortable with de-escalated elective volumes (we use 30 Gy for HPV-positive and 40 Gy for HPV-negative non-oral cavity disease), then this would be a reasonable situ...

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