In what situations should chemotherapy be added to adjuvant radiation therapy in a resected vuvlar SCC?

We did analysis from NCDB and saw significant trend of use of concurrent chemotherapy for node positive disease and its positive impact on survival. That being said these studies have their own flaws. In practice we do add concurrent cisplatinum for node positive patients if performance status allow...

I agree with Sushil. We usually add chemo for node positive vulvar cancer patients. However, given the relative lack of strong evidence, this must be balanced with potential morbidity particularly for frail elderly patients. We would prefer to treat adjuvantly with RT alone than to have protracted o...