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In what situations would a standard FDG PET/CT be useful in the evaluation of high risk prostate cancer?

With the advent of PSMA PET/CT, this is my study of choice for high risk prostate cancer. Are there scenarios where standard FDG PET is useful? For example, Gleason 5, dedifferentiated tumors, or those with an intraductal component?
4 Answers
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Radiation Oncology
Answered on

Overall, my impression is that the use of FDG PET for this purpose is limited. If interested, below is my rationale as summarized in the Conclusion.

As mentioned, PSMA PET/CT is considered by many to be the current best standard of care for the staging evaluation of high-risk prostate cancer, and it ...

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Radiation Oncology · Cedars-Sinai Medical Center
Answered on

I would also consider an FDG PET/CT in addition to a PSMA PET/CT for nodal and distant staging work-up of a prostate adenocarcinoma with neuroendocrine differentiation.

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Radiation Oncology · University of Florida
Answered on

Mostly to identify positive nodes

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Radiation Oncology · Allegheny General Hospital-Western Pennsylvania Hospital
Answered on

I’ve found it useful for ductal histology.

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