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In what situations would you treat elective regional lymph nodes for a squamous cell carcinoma of the skin on the extremity/trunk that was clinically node negative?

For example, for a squamous cell carcinoma of the forearm treated with Mohs surgery with negative margins, are there features that would lead you to electively treat the epitrochlear and/or axillary nodes, (e.g. size, DOI, PNI, or an immunosuppressed patient)?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · University of Oklahoma College of Medicine
Answered on

Nodal metastasis from small, to medium size [up to 3 cm in diameter] squamous cell carcinoma on the extremity is not that common. Considering the morbidity of nodal treatment in a patient with clear margins of resection I would not prophylactically treat the nodes. If the tumor shows perineural or l...

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