In which patients do you prefer daily standard three-drug therapy for non-cavitary pulmonary MAC as opposed to three times a week dosing?

Generally, if non-cavitary disease I favor thrice weekly therapy. However, if widespread non cavitary disease or immunosuppressed, I may choose daily dosing.

I tend to always recommend daily therapy unless the patient has a strong preference for it. Personally, I think it's easier to remember a daily dose, and it's a more effective regimen, at least for cavitary disease.