In which patients with CHE will you prioritize early use of delgocitinib?   

I can't think of any that I'd prioritize specifically compared to other patients. Trial of high-potency topical steroids, then Anzupgo next visit if not doing great. Other key point is to stop the steroid when you start the Anzupgo - topical steroids have a very strong negative impact on barrier fun...

I think about delgocitinib early in patients with recurrent flares, lack of efficacy or adverse events with steroids, or those with a significant impact on daily function or work ability. I would consider skipping steroids entirely, but typically, when I see patients, they have already tried topical...