The controversy on contralateral neck disease is whether this is impacted by efferent lymphatics from the primary or collateral flow in the neck from involved nodes.Thus with regards to the primary tonsil cancers that are T1,T2 well lateralized without involvement of the base of tongue nor soft pala...

T1-T2 N0-N1 tonsil with less than 1 cm soft palate or base of tongue invasion. Perhaps you could use this thought process to say, very lateralized base of tongue tumor but there is really no evidence for this, other than emerging retrospective TORS series where these are being treated with ipsilater...

The classical report showing the safety of unilateral RT of OPC was by Brian O'Sullivan, demonstrating lack of contralateral recurrences in patients with early OPC. They used ipsilateral wedge-pair photons causing significant contralateral neck exit doses, in an era when non-HPV,...

For HPV+ pT1-2 N2a patients who are otherwise eligible for unilateral radiotherapy, does the presence of either microscopic extranodal extension (<=2 mm) or larger nodal size (e.g., >4 cm) impact your decision making about offering unilateral radiotherapy?  From my review of literature t...