In which Sjogren's patients do you prioritize systemic treatment strategies at time of diagnosis?   

Answering this question would really depend on what exact type of patient you are dealing with. You may consider initiating oral DMARDs such as hydroxychloroquine, methotrexate, or azathioprine for patients with inflammatory arthropathy or significant autoimmune rashes. More aggressive therapy would...

Tough to give a general answer, but obviously SjD with vasculitis (not just limited to skin). The other phenotypes would depend on the severity of disease activity, potential risk of damage, and assessment of potential reversibility (vs damage with ongoing immune-mediated disease). The main domains ...