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Is a tumor ever too small to send off a genomic assay like Oncotype or Mammoprint in HR positive, HER2 negative stage 1 breast cancer?

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Do you routinely perform predictive genomic assays for low risk tumors (HR positive, Her2 negative, Grade 1 without LVI) even when its a T1b lesion?

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1 Answer
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Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on · Updated on

The Oncotype DX has been used to identify high risk stage T1b tumors that may benefit from the addition of chemotherapy such as Taxotere/Cytoxan for 4 cycles and has been part of NCCN guidelines for quite some time. We do consider chemotherapy for high risk T1b luminal B tumors (either on basis of h...

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