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Is inositol just as effective as metformin in treating insulin resistance associated with PCOS?

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Do you recommend the use of myo-inositol for treatment of insulin resistance associated with PCOS in patients who are intolerant to metformin?

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3 Answers
Mednet Member
Mednet MemberInvited Expert
Endocrinology · Brigham And Womens Hospital Endocrinology
Answered on

Myo-inositol (MYI) and its metabolite D-chiro inositol (DCI) are over-the-counter
supplements that have been suggested to improve insulin action in patients with PCOS. Outside of the PCOS world, there doesn’t seem to be much traction to using MYI over metformin for pre-diabetes and I believe it is no...

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Mednet Member
Mednet Member
Endocrinology · Cooper University
Answered on

In patients with normal A1c’s I’ve had good experience with D-chiral inositol for managing the other symptoms of PCOS (cycle regularly, anxiety, etc).

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Mednet Member
Mednet MemberInvited Expert
Endocrinology · Michigan State University College of Human Medicine
Answered on

I have no experience with Myoinositol and DCI.

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