Is inositol just as effective as metformin in treating insulin resistance associated with PCOS?
Do you recommend the use of myo-inositol for treatment of insulin resistance associated with PCOS in patients who are intolerant to metformin?
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Myo-inositol (MYI) and its metabolite D-chiro inositol (DCI) are over-the-counter
supplements that have been suggested to improve insulin action in patients with PCOS. Outside of the PCOS world, there doesn’t seem to be much traction to using MYI over metformin for pre-diabetes and I believe it is not as effective for the metabolic consequences of insulin resistance in the general population, or we would see more positive studies. There are studies, however, in PCOS patients that have looked at m...
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In patients with normal A1c’s I’ve had good experience with D-chiral inositol for managing the other symptoms of PCOS (cycle regularly, anxiety, etc).
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I have no experience with Myoinositol and DCI.
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