Mednet Logo
CommunityPulmonology

Is it safe to combine mycophenolate and adalimumab for management of pulmonary sarcoidosis in a patient that could not tolerate methotrexate?

3 Answers
Mednet Member
Mednet MemberInvited Expert
Rheumatology · Virginia Commonwealth University Health System
Answered on

Combination therapy is often required in patients with sarcoidosis. Combination of adalimumab with other immunosuppressants, such as methotrexate, leflunomide, azathioprine, or mycophenolate, can be used, with close monitoring of labs (CBC, CMP) and for infections.

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Pulmonology · Rush University Medical Center
Answered on

Data are limited but the combination of adalimumab and mycophenolate (or other immunosuppressive medications) appears to be safe and effective in various forms of sarcoidosis (Sweiss et al., PMID 24751453, Metyas et al., PMID 24576278, Miller et al., PMID 26828145, Villacis-Nunez & Thakral, PMID 339...

Join for free or sign in to see the full answer

Mednet Member
Mednet Member
Rheumatology · University of Chicago
Answered on

What is the reason the patient needs a DMARD?

Join for free or sign in to see the full answer