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Is it safe to re-irradiate the pelvis after definitive prostate brachytherapy?

Eight years after brachytherapy for a low risk prostate cancer, a patient has unresectable high grade squamous cell carcinoma of the bladder. Should I offer palliative EBRT? What dose and fractionation? Are there any data regarding toxicities in this situation?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · UCLA | VA Greater Los Angeles Healthcare System
Answered on

Evaluating the brachytherapy dosimetery can be very useful here. It will provide a visual reminder of how conformal such tx can be. The bladder was likely not exposed. Next, if brachytherapy planning software is available, the doses could be reconstructed and superimposed on the new CT sim (if impla...

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