Is it safe to use medroxyprogesterone for vasomotor flushing?

There are many options for management of hot flashes including venflaxine and gabapentin being most frequently used as well as some data on cognitive behavioral therapy, oxybutynin, and acupuncture. For the most refractory cases, I do discuss medoroxyprogesterone 400 mg IM as a one time option based...

One must remember that progesterone (Medroxyprogesterone acetate) is actually a treatment for metastatic ER+ Breast cancer. In addition, the Loprinzi study showed no adverse effects on breast cancer disease status.