Is the adage “If GCS <8, intubate” still relevant for non-TBI patients?

It's a challenging area. NICO does lead credence to withholding intubation among patients that are comatose from acute poisoning with improvements in "composite end point of in-hospital death, length of ICU stay, and length of hospital stay."

Practically speaking, I've never liked hard and fast rules...

I’ve seen too many patients harmed by getting intubated for the hard rule of GCS <8. The clinical context and history matters more than a number.